About employee

izv. prof. dr. sc. Jasmina Rokov Plavec

Title: Associate Professor
Location: 306/ZBK
Public phone number:+385 1 4606 232
Internal phone number:6232
E-mail: E-mail
Official web page URL: http://www.pmf.unizg.hr/chem/jasmina.rokov_plavec
Department: Division of Biochemistry
Graduation year:1994
mr.sc. graduation year:1998
PhD graduation year:2004
Employed in this institution since:1995

Teaching

undergraduate

graduate

integrated undergraduate and graduate

doctoral

Biography

Education at Department of Biology, Faculty of Science, University of Zagreb: Diploma thesis (Molecular Biology, 1994); Master thesis (Biology, Molecular and Cellular Biology, 1998); Doctoral thesis (Biology, 2004).  

Affiliation and current position: Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb: Associate Professor (2024 –).  

Previous positions: Assistant Professor (2008-2024); Senior Assistant (2005-2008); Assistant (1995-2005), Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb.  

Teaching: Lectures in Biochemistry, Biochemistry 1 (for students of biology and chemistry), Biochemistry 2 (for molecular biology students), Genetic and protein engineering (for students of chemistry)

Visits to foreign research and education institutions: Central European Institute of Technology, Brno, Czech Republic, duration: two weeks in 2019; Department of Biochemistry and Molecular Biophysics, Yale University, USA, duration: two months in 1998; Institut de Biologie Moléculaire des Plantes du CNRS, Strasbourg, France, duration: two months in 2006  

Research interest: I’m interested in structure, function and evolution of aminoacyl-tRNA synthetases with emphasis on plant seryl-tRNA synthetases (SerRS). I study intracellular localization of proteins, role of plant SerRS in cellular stress response and identification and characterization of SerRS protein interactors. Additionaly, I'm interested in adaptation of bacterial cells to oxidative stress due to erors in translation.

Scientific papers: Author of 19 original scientific papers, 2 professional papers, 2 chapters in the university textbook, 3 laboratory manuals.  

Mentoring: 2 PhD student, 12 Master students, 38 BSc students

Awards, recognitions and memberships: Rector's award of the University of Zagreb for the year 1993. Member of the Croatian Society for Biochemistry and Molecular Biology (since 1997). Member of the executive board of Croatian Society for Biochemistry and Molecular Biology (2013-2021). Co-leader of "Young investigators", section of Croatian Natural History Society in 1997/1998; 2018 - 2020 head of the Division of Biochemistry; head of the Laboratory for Enzyme Kinetics and Preparative Biochemistry within the Center of Excellence in Chemistry (CIuK) at the Department of Chemistry (since 2021); member of the Quality Management Committee of the Faculty of Science (since 2021).  

Participation in research projects:  

Project leader:  

1. Young Researchers’ Career Development Project - training new doctoral students, Croatian Science Foundation, 2019-2024, mentor of PhD student

2. Functional and structural characterization of protein complexes of plant aminoacyl-tRNA synthetase, Foundation of Croatian Academy of Sciences and Arts, 2018-2019  

3. Interplay of protein biosynthesis and steroid hormone metabolism in plants, Foundation of Croatian Academy of Sciences and Arts, 2016-2017  

4. Role of plant aminoacyl-tRNA synthetase in cellular stress response, Foundation of Croatian Academy of Sciences and Arts, 2014-2015  

Co-leader of work package:  

INTEGRA-LIFE, FP7-REGPOT, PI: Gordan Lauc, 2013-2016  

Project participant:

1. Aminoacyl-tRNA synthetases as gatekeepers of the genetic code, Croatian Science Foundation, PI: Ita Gruić Sovulj, 2017-2021

2. COST Action CA15126 Between Atom and Cell: Integrating Molecular Biophysics Approaches for Biology and Healthcare (MOBIEU), PI: Patrick England, 2016-2020

3. Non-canonical roles of aminoacyl-tRNA synthetases, Croatian Science Foundation, PIs: Ivana Weygand-Đurašević and Ita Gruić Sovulj, 2013-2016 

4. Structural diversity of seryl-tRNA synthetases and accuracy of protein synthesis, Ministry of Science, Education and Sports of the Republic of Croatia, PI: Ivana Weygand-Đurašević, 2007- 2014  

5. Macromolecular complexes of aminoacyl-tRNA synthetases and their role in translational quality control and non-ribosomal peptide synthesis, UKF, PI: Ivana Weygand-Đurašević, 2007-2010  

6. Quality control mechanisms in seryl-tRNA biosynthesis, Ministry of Science, Education and Sports of the Republic of Croatia, PI: Ivana Weygand-Đurašević, 2002-2007  

7. Structure, function and evolution of aminoacyl-tRNA synthetases, Ministry of Science, Education and Sports of the Republic of Croatia, PI: Ivana Weygand-Đurašević, 1996-2002

Published papers recorded in the Croatian Scientific Bibliography Database

Interplay between mistranslation and oxidative stress in Escherichia coli

Ević, Valentina; Rokov Plavec, Jasmina
2024.
Arhiv za higijenu rada i toksikologiju

Laboratory course “From gene to recombinant protein“

Rokov Plavec, Jasmina; Močibob, Marko
2024.

Disulfide link in plant cytosolic aminoacyl-tRNA synthetase is implicated in oxidative stress response

Rokov Plavec, Jasmina; Ević, Valentina; Močibob, Marko; Šoić, Ružica; Kekez, Ivana
2024.

Interplay of isoleucine mistranslation and oxidative stress from a proteomic perspective

Šerić, Mateo; Močibob, Marko; Rokov Plavec, Jasmina
2024.

Disulfide bond enables cytosolic protein to function in oxidizing conditions

Rokov Plavec, Jasmina; Ević, Valentina; Šoić, Ružica; Močibob, Marko; Kekez, Ivana
2024.

Protein–Protein Interactions of Seryl-tRNA Synthetases with Emphasis on Human Counterparts and Their Connection to Health and Disease

Dulic, Morana; Godinic-Mikulcic, Vlatka; Kekez, Mario; Evic, Valentina; Rokov-Plavec, Jasmina
2024.
Life

Evolutionarily conserved cysteines in plant cytosolic seryl-tRNA synthetase are important for its resistance to oxidation

Evic, Valentina; Soic, Ruzica; Mocibob, Marko; Kekez, Mario; Houser, Josef; Wimmerova, Michaela; Matković-Čalogović, Dubravka; Gruic-Sovulj, Ita; Kekez, Ivana; Rokov-Plavec, Jasmina
2023.
FEBS letters

Uloga disulfidne veze u biljnoj citosolnoj seril-tRNA-sintetazi

Rokov Plavec, Jasmina; Ević, Valentina; Kekez, Ivana; Šoić, Ružica; Močibob, Marko
2023.

Beneficial effect of mistranslation on proliferation and viability of bacteria Escherichia coli in oxidative stress

Ević, Valentina ; Peharec Štefanić, Petra ; Gruić Sovulj, Ita ; Rokov Plavec, Jasmina
2022.

Mistranslation helps Escherichia coli to adapt to oxidative stress

Ević, Valentina ; Peharec Štefanić, Petra ; Gruić Sovulj, Ita ; Rokov Plavec, Jasmina
2022.
FEBS Open Bio

Contrasting effect of evolutionary conserved cysteines on the stability of plant seryl-tRNA synthetase

Ević, Valentina ; Šoić, Ružica ; Matković-Čalogović, Dubravka ; Gruić Sovulj, Ita ; Kekez, Ivana ; Rokov Plavec, Jasmina
2022.

The role of mistranslation in oxidative stress response in bacteria Escherichia coli

Ević, Valentina ; Peharec Štefanić, Petra ; Gruić Sovulj, Ita ; Rokov Plavec, Jasmina
2022.

Importance of protein intrinsic conformational dynamics and transient nature of non-covalent interactions in ligand binding affinity

Kekez, Mario ; Zanki, Vladimir ; Antičević, Ivan ; Rokov-Plavec, Jasmina ; Maršavelski, Aleksandra
2021.
International journal of biological macromolecules

Effect of mistranslation and oxidative stress on growth and viability of bacteria Escherichia coli

Ević, Valentina ; Gruić Sovulj, Ita ; Rokov Plavec, Jasmina
2021.

Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

López-Méndez, Blanca ; Baron, Bruno ; Brautigam, Chad A. ; Jowitt, Thomas A. ; Knauer, Stefan H. ; Uebel, Stephan ; Williams, Mark A. ; Sedivy, Arthur ; Abian, Olga ; Abreu, Celeste ; Adamczyk, Malgorzata ; Bal, Wojciech ; Berger, Sylvie ; Buell, Alexander K. ; Carolis, Carlo ; Daviter, Tina ; Fish, Alexander ; Garcia-Alai, Maria ; Guenther, Christian ; Hamacek, Josef ; Holková, Jitka ; Houser, Josef ; Johnson, Chris ; Kelly, Sharon ; Leech, Andrew ; Mas, Caroline ; Matulis, Daumantas ; McLaughlin, Stephen H. ; Montserret, Roland ; Nasreddine, Rouba ; Nehmé, Reine ; Nguyen, Quyen ; Ortega-Alarcón, David ; Perez, Kathryn ; Pirc, Katja ; Piszczek, Grzegorz ; Podobnik, Marjetka ; Rodrigo, Natalia ; Rokov- Plavec, Jasmina ; Schaefer, Susanne ; Sharpe, Tim ; Southall, June ; Staunton, David ; Tavares, Pedro ; Vanek, Ondrej ; Weyand, Michael ; Wu, Di
2021.
European biophysics journal

Expression of genes for selected plant aminoacyl-tRNA synthetases in the abiotic stress

Baranašić, Jurica ; Mihalak, Anita ; Gruić Sovulj, Ita ; Bauer, Nataša ; Rokov Plavec, Jasmina
2021.
Acta botanica Croatica

Influence of mistranslation stress on oxidative stress response in bacteria Escherichia coli

Ević, Valentina ; Gruić Sovulj, Ita ; Rokov- Plavec, Jasmina
2021.
FEBS Open Bio

Emerging noncanonical functions of plant aminoacyl- tRNA synthetase

Rokov Plavec, Jasmina ; Kekez, Mario ; Ević, Valentina ; Zanki, Vladimir ; Šoić, Ružica ; Matković-Čalogović, Dubravka ; Kekez, Ivana
2021.
FEBS Open Bio

Importance of the disulfide link in the stability of cytosolic protein

Rokov Plavec, Jasmina ; Ević, Valentina ; Kekez, Mario ; Kekez, Ivana ; Šoić, Ružica ; Houser, Josef ; Wimmerová, Michaela ; Matković-Čalogović, Dubravka
2020.

Plant seryl-tRNA synthetase as a link between translation and metabolism of brassinosteroid hormones

Rokov Plavec, Jasmina ; Kekez, Mario ; Zanki, Vladimir ; Kekez, Ivana ; Matković-Čalogović, Dubravka
2019.

Is expression of VEGFA gene regulated by seryl-tRNA synthetase in renal cell carcinoma?

Barači, Maja ; Knezović Florijan, Marijana ; Ozretić, Petar ; Kaštelan, Željko ; Slade, Neda ; Rokov Plavec, Jasmina ; Hudolin, Tvrtko
2019.

Arabidopsis seryl-tRNA synthetase: the first crystal structure and novel protein interactor of plant aminoacyl-tRNA synthetase

Kekez, Mario ; Zanki, Vladimir ; Kekez, Ivana ; Baranašić, Jurica ; Hodnik, Vesna ; Duchêne, Anne- Marie ; Anderluh, Gregor ; Gruić Sovulj, Ita ; Matković-Čalogović, Dubravka ; Weygand-Đurašević, Ivana ; Rokov Plavec, Jasmina
2019.
The FEBS journal

Plant seryl-tRNA synthetase as a link between translation and metabolism of brassinosteroid hormones

Kekez, Mario ; Zanki, Vladimir ; Kekez, Ivana ; Matković-Čalogović, Dubravka ; Rokov Plavec, Jasmina
2019.

Revealing the structure of the first plant aminoacyl-tRNA synthetase at 2.3 Å

Kekez, Ivana ; Kekez, Mario ; Stojanović, Mario ; Rokov-Plavec, Jasmina ; Matković-Čalogović, Dubravka
2018.

Where translation meets plant steroid metabolism: interaction of seryl-tRNA synthetase and BEN1 protein from Arabidopsis thaliana

Kekez, Mario ; Zanki, Vladimir ; Kekez, Ivana ; Matković-Čalogović, Dubravka ; Rokov-Plavec, Jasmina
2018.

Plant aminoacyl-tRNA synthetases in abiotic stress

Baranasic, Jurica ; Kekez, Mario ; Mihalak, Anita ; Jasmina, Rokov Plavec
2018.

The first crystal structure of plant aminoacyl-tRNA synthetase: seryl-tRNA synthetase from Arabidopsis thaliana

Kekez, Ivana ; Kekez, Mario ; Rokov-Plavec, Jasmina ; Gruić-Sovulj, Ita ; Matković-Čalogović, Dubravka
2016.

Dizajniranje proteina

Rokov Plavec, Jasmina
2016.
Priroda (Zagreb)

Viši praktikum kemije (interna skripta za studente sveučilišnog diplomskog studija Kemija, smjer nastavnički)

Popović, Zora ; Prugovečki, Biserka, Juranović Cindrić, Iva ; Ribić, Rosana ; Rokov Plavec, Jasmina ; Preočanin, Tajana ; Bregović, Nikola
2016.

Dysregulation of seryl-tRNA synthetase in kidney disease

Barači, Maja ; Knezović, Marijana ; Majić, Željka ; Slade, Neda ; Kaštelan, Željko ; Hudolin, Tvrtko ; Rokov Plavec, Jasmina ; Gruić Sovulj, Ita
2016.

Seryl-tRNA Synthetases in Translation and Beyond

Močibob, Marko ; Rokov-Plavec, Jasmina ; Godinić- Mikulčić, Vlatka ; Gruić-Sovulj, Ita
2016.
Croatica chemica acta

Interplay of proteins involved in translation and steroid hormone metabolism in Arabidopsis

Rokov Plavec, Jasmina ; Kekez, Mario ; Zanki, Vladimir ; Bauer, Nataša
2016.

Exclusive cytosolic localization and broad tRNASer specificity of Arabidopsis thaliana seryl-tRNA synthetase

Kekez, Mario ; Bauer, Nataša ; Šarić, Ela ; Rokov- Plavec, Jasmina
2016.
Journal of plant biology

Structural study of atypical seryl-tRNA synthetase protein complex

Godinić Mikulčić, Vlatka ; Sviben, Igor ; Rokov- Plavec, Jasmina ; Gruić-Sovulj, Ita
2015.

Plant seryl-tRNA synthetase and metabolic protein BEN1: identification of interaction surfaces by biophysical methods

Kekez, Mario ; Zanki, Vladimir ; Hodnik, Vesna ; Anderluh, Gregor ; Rokov Plavec, Jasmina
2015.

Fluorescence approach for determination of ribosomal L12 protein binding domains involved in interaction with seryl-tRNA synthetase

Godinić Mikulčić, Vlatka ; Sviben, Igor ; Rokov- Plavec, Jasmina ; Gruić-Sovulj, Ita
2015.

Analysis of protein interactions using fluorescence technologies

Godinić Mikulčić, Vlatka ; Sviben, Igor ; Janeš, Karla ; Kveštak, Martina ; Rokov-Plavec, Jasmina ; Gruić-Sovulj, Ita
2015.

Pinpointing the interaction domains of plant seryl- tRNA synthetase and metabolic protein BEN1

Kekez, Mario ; Zanki, Vladimir ; Hodnik, Vesna ; Anderluh, Gregor ; Duchêne, Anne-Marie ; Rokov Plavec, Jasmina
2015.

Noncanonical interactions of plant seryl-tRNA synthetase

Kekez, Mario ; Bauer, Nataša ; Hodnik, Vesna ; Anderluh, Gregor ; Duchêne, Anne-Marie ; Rokov Plavec, Jasmina
2015.

Arabidopsis thaliana seryl-tRNA synthetase participates in cellular stress response

Rokov Plavec, Jasmina ; Kekez, Mario ; Bauer, Nataša ; Šarić, Ela ; Weygand-Đurašević, Ivana
2014.

Interaction of plant seryl-tRNA synthetase and BEN1, protein involved in brassinosteroid metabolism

Kekez, Mario ; Rokov-Plavec, Jasmina ; Hodnik, Vesna ; Anderluh, Gregor ; Weygand-Đurašević, Ivana
2014.

In vivo and in vitro analysis of plant seryl-tRNA synthetase interactome

Kekez, Mario ; Rokov Plavec, Jasmina ; Bauer, Nataša ; Razdorov, Genadij ; Hodnik, Vesna ; Anderluh, Gregor ; Weygand-Đurašević, Ivana
2014.

Arabidopsis thaliana cytosolic seryl-tRNA synthetase: studying protein-protein interactions

Kekez, Mario ; Rokov-Plavec, Jasmina ; Bauer, Nataša ; Razdorov, Genadij ; Weygand-Đurašević, Ivana
2013.

Substrate recognition and fidelity of maize seryl- tRNA synthetases

Rokov-Plavec, Jasmina ; Lesjak, Sonja ; Gruić- Sovulj, Ita ; Močibob, Marko ; Dulić, Morana ; Weygand-Đurašević, Ivana
2013.
Archives of biochemistry and biophysics

Plant seryl-tRNA synthetases : fidelity and macromolecular recognition

Rokov Plavec, Jasmina ; Lesjak, Sonja ; Gruić Sovulj, Ita ; Močibob, Marko ; Dulić, Morana ; Kekez, Mario ; Bauer, Nataša ; Weygand-Đurašević, Ivana
2012.

Dual targeting of organellar seryl-tRNA synthetase to maize mitochondria and chloroplasts

Rokov-Plavec, Jasmina ; Dulić, Morana ; Duchene, Anne-Marie ; Weygand-Durasevic, Ivana
2008.
Plant cell reports

Structural flexibility of the methanogenic-type seryl-tRNA synthetase active site and its implication for specific substrate recognition

Bilokapić, Silvija ; Rokov-Plavec, Jasmina ; Ban, Nenad ; Weygand-Đurašević, Ivana
2008.
The FEBS journal

Nobelova nagrada za kemiju 2008.

Dulić, Morana ; Rokov-Plavec, Jasmina
2008.
Kemija u industriji : časopis kemičara i tehnologa Hrvatske

Hydrolysis of non-cognate aminoacyl-adenylates by a class II aminoacyl-tRNA synthetase lacking an editing domain

Gruić-Sovulj, Ita ; Rokov-Plavec, Jasmina ; Weygand- Đurašević, Ivana
2007.
FEBS letters

Izdvajanje mitohondrija iz gomolja krumpira

Rokov-Plavec, Jasmina
2007.

Izdvajanje ukupne tRNA

Močibob, Marko ; Rokov-Plavec, Jasmina
2007.

Amber suppression in bacterium Escherichia coli using archaeal ortologous seryl-tRNA

Lesjak, Sonja ; Boko, Draško ; Rokov-Plavec, Jasmina ; Weygand-Đurašević, Ivana
2004.

Unilateral flexibility in tRNASer recognition by heterologous seryl-tRNA synthetases

Rokov-Plavec, Jasmina ; Bilokapić, Silvija ; Gruić-Sovulj, Ita ; Močibob, Marko ; Glavan, Filip ; Brgles, Marija ; Weygand-Đurašević, Ivana
2004.
Periodicum biologorum

Stability of the complex between yeast seryl- tRNA synthetase and tRNASer under different electrophoretic conditions

Gruić-Sovulj, Ita ; Rokov-Plavec, Jasmina ; Močibob, Marko ; Kamenski, Tomislav ; Weygand- Đurašević, Ivana
2004.
Croatica chemica acta

In vivo recognition of eukaryal and bacterial tRNAsSer by heterologous seryl-tRNA synthetases

Lesjak, Sonja ; Rokov, Jasmina ; Landeka, Irena ; Weygand-Đurašević, Ivana
2003.

Seryl-tRNA syntheases: Structure, function and evolution across all three domains of life

Rokov Plavec, Jasmina ; Ročak, Sanda ; Gruić-Sovulj, Ita ; Landeka, Irena ; Lesjak, Sonja ; Jarić, Jelena ; Močibob, Marko ; Bilokapić, Silvija ; Weygand-Đurašević, Ivana
2003.

Maize seryl-tRNA synthetase: specificity of substrate recognition by the organellar enzyme

Rokov-Plavec, Jasmina ; Lesjak, Sonja ; Landeka, Irena ; Mijaković, Ivan ; Weygand-Đurašević, Ivana
2002.
Archives of biochemistry and biophysics

Organellar and cytosolic seryl-tRNA synthetases: structural, functional and evolutionary aspects

Weygand-Đurašević, Ivana ; Lenhard, Boris ; Ročak, Sanda ; Rokov, Jasmina ; Landeka, Irena ; Mijaković, Ivan
2000.
Acta biologica slovenica

Structure, function and evolution of aminoacyl-tRNA synthetases

Rokov-Plavec, Jasmina ; Landeka, Irena ; Mijaković, Ivan ; Muštra, Sonja ; Gruić-Sovulj, Ita ; Ročak, Sanda ; Weygand-Đurašević, Ivana
2000.

Evolution of determinants in seryl-tRNA synthesis

Gruić-Sovulj, Ita ; Landeka, Irena ; Ročak, Sanda ; Rokov-Plavec, Jasmina ; Muštra, Sonja ; Lenhard, Boris ; Weygand-Đurašević, Ivana
2000.

Seryl-tRNA synthesis in maize

Rokov, Jasmina ; Weygand-Đurašević, Ivana
1999.
Periodicum biologorum

ENGINEERING OF AMINOACYLATION SYSTEM: SPECIFICITY OF INTERACTIONS AND STRUCTURE-BASED DESIGN

Filipić, Sanda ; Landeka, Irena ; Lenhard, Boris ; Mijaković, Ivan ; Rokov, Jasmina ; Weygand-Đurašević, Ivana
1999.

Phylogenetic relationships and early evolutionary events in seryl-tRNA synthetases

Lenhard, Boris ; Rokov, Jasmina ; Filipić, Sanda ; Weygand-Đurašević, Ivana
1998.

MAIZE SERYL-tRNA SYNTHETASES FROM DIFFERENT CELLULAR COMPARTMENTS

Rokov, Jasmina ; Petranović, Dina ; Lenhard, Boris ; Weygand-Đurašević, Ivana
1998.

Maize mitochondrial seryl-tRNA synthetase recorgnizes Escherichia coli tRNASer in vivo and in vitro

Rokov, Jasmina ; Soll, Dieter ; Weygand-Đurašević, Ivana
1998.
Plant molecular biology

Functional and evolutionary analysis of organellar seryl-tRNA synthetases

Mijaković, Ivan ; Lenhard, Boris ; Rokov, Jasmina ; Weygand-Đurašević, Ivana
1998.

MITOCHONDRIAL AND CYTOPLASMIC SERYL-tRNA SYNTHETASES FROM Zea mays

Rokov, Jasmina ; Lenhard, Boris ; Filipić, Sanda ; Mijaković, Ivan ; Weygand-Đurašević, Ivana
1998.

tRNA dependent amino acid recognition by yeast seryl-tRNA synthetase

Lenhard, Boris ; Filipić, Sanda ; Rokov, Jasmina ; Weygand-Đurašević, Ivana
1997.

SerZMo gene codes for maize organellar seryl-tRNA synthetase

Rokov, Jasmina ; Čajavec, Branka ; Lenhard, Boris ; Weygand-Đurašević, Ivana
1997.

Strutural and functional relationship among cytoplasmic and mitochondrial seryl-tRNA synthetases

Lenhard, Boris ; Filipić, Sanda ; Rokov, Jasmina ; Landeka, Irena ; Soell, Dieter ; Weygand-Đurašević, Ivana
1997.
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