About employee

dr. sc. Igor Živković

Title: Senior research assistant
Location: 312/ZBK
Public phone number:+385 1 4606 234
Internal phone number:6234
E-mail: E-mail
Personal web page: http://gruic.chem.pmf.unizg.hr/people/phd/#zivkovic
Department: Division of Biochemistry
Graduation year:2016
PhD graduation year:2021
Employed in this institution since:2016

Biography

Education at the Department of Chemistry, Faculty of Science, University of Zagreb: Bachelor's degree in Chemistry (2014), Master's degree in Chemistry (2016), PhD in Chemistry (2021).

Affiliation and current position: Division of Biochemistry, Department of Chemistry, Faculty of Science, University of Zagreb: Research Assistant (2016 - 2022), Postdoc (2022 - ).

Teachings: General biochemistry (seminars) and Biochemistry laboratory (practicum courses).

Research interest: Reaction of aminoacyl-tRNA synthetases with natural and synthetic non-cognate substrates, substrate specificity, kinetics

Memberships: Member of the Croatian Chemical Society Croatian Society of Biochemistry and Molecular Biology.

Published papers recorded in the Croatian Scientific Bibliography Database

Exploring mechanisms of mupirocin resistance and hyper-resistance

Živković, Igor; Gruić Sovulj, Ita
2024.
Biochemical Society transactions

HOW DID NEGATIVE CATALYSIS TAILOR THE SPECIFICITY OF ISOLEUCYL-tRNA SYNTHETASES’S EDITING DOMAIN?

Živković, Igor; Maršavelski, Aleksandra; Gruić-Sovulj, Ita
2024.

Kinetic characterization of amino acid activation by aminoacyl‐tRNA synthetases using radiolabelled γ‐[32P]ATP

Živković, Igor; Dulić, Morana; Kozulić, Petra; Močibob, Marko; Gruić Sovulj, Ita
2024.
FEBS Open Bio

Environmental implications of dental restorative materials on the zebrafish Danio rerio: Are dental chair drainage systems an emerging environmental threat?

Majstorović, Matea; Babić Brčić, Sanja; Malev, Olga; Par, Matej; Živković, Igor; Marciuš, Marijan; Tarle, Zrinka; Čož-Rakovac, Rozelindra; Marović, Danijela
2024.
Environmental toxicology and pharmacology

ALL BUT ONE: HOW NEGATIVE CATALYSIS SHAPED EVOLUTION OF THE ISOLEUCYL-TRNA SYNTHETASE'S EDITING DOMAIN

Živković, Igor ; Maršavelski, Aleksandra, Gruić- Sovulj, Ita
2022.

Negative catalysis by the editing domain of class I aminoacyl-tRNA synthetases

Živković, Igor ; Ivković, Kate ; Cvetešić, Nevena ; Maršavelski, Aleksandra ; Gruić Sovulj, Ita
2022.
Nucleic acids research

Mechanism of discrimination of isoleucyl-tRNA synthetase against nonproteinogenic a- aminobutyrate and its fluorinated analogues

Živković, Igor ; Moschner, Johann ; Koksch, Beate ; Gruić Sovulj, Ita
2020.
The FEBS journal

Maintaining the protein biosynthesis fidelity by isoleucyl-tRNA synthetase

Močibob, Marko ; Biluš, Mirna ; Šemanjski, Maja ; Živković, Igor ; Cvetešić, Nevena ; Maček, Boris ; Gruić Sovulj, Ita
2019.

On the Mechanism and Origin of Isoleucyl-tRNA Synthetase Editing against Norvaline

Biluš, Mirna ; Šemanjski, Maja ; Močibob, Marko ; Živković, Igor ; Cvetešić, Nevena ; Tawfik, Dan ; Toth-Petroczy, Agnes ; Maček, Boris ; Gruić-Sovulj, Ita
2019.
Journal of molecular biology

Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase

Dulić, Morana ; Cvetešić, Nevena ; Živković, Igor ; Palencia, Andrés ; Cusack, Stephen ; Bertoša, Branimir ; Gruić-Sovulj, Ita
2018.
Journal of molecular biology

Trimming a branch: norvaline is more toxic than valine in isoleucine mistranslation

Biluš, Mirna ; Šemanjski, Maja ; Močibob, Marko ; Živković, Igor ; Cvetešić, Nevena ; Tawfik, Dan ; Toth-Petroczy, Agnes ; Gruić-Sovulj, Ita
2018.

Exclusion of the cognate substrate from the leucyl - tRNA synthetase editing pathway

Živković, Igor ; Dulić, Morana ; Cvetešić, Nevena ; Bertoša, Branimir ; Gruić-Sovulj, Ita
2017.
More information about publications

List of select publications

1. Živković I., Ivković K., Cvetešić N., Maršavelski A., Gruić Sovulj I., Negative catalysis by the editing domain of class I aminoacyl-tRNA synthetases; Nucleic Acids Research, 50 (2022) 4029-4041. (IF = 16,971); doi:10.1093/nar/gkac207

2. Živković I., Moschner J., Koksch B., Gruić Sovulj I., Mechanism of discrimination of isoleucyl-tRNA synthetase against nonproteinogenic α-aminobutyrate and its fluorinated analogues; The FEBS Journal, 287 (2020) 800-813. (IF = 5,542); doi:10.1111/febs.15053

3. Biluš M., Šemanjski M., Močibob M., Živković I., Cvetešić N., Tawfik D., Toth-Petroczy A., Maček B., Gruić Sovulj I., On the mechanism and origin of isoleucyl-tRNA synthetase editing against norvaline, Journal of Molecular Biology, 431 (2019) 1284-1297. (IF = 5,469); doi:10.1016/j.jmb.2019.01.029

4. Dulić M., Cvetešić N., Živković I., Palencia A., Cusack S., Bertoša B., Gruić Sovulj I., Kinetic origin of substrate specificity in post-transfer editing by leucyl-tRNA synthetase, Journal of Molecular Biology, 430 (2018) 1-16. (IF = 5,469); doi:10.1016/j.jmb.2017.10.024